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VBI offers fellowships for
graduate work in
transdisciplinary studies
The Virginia Bioinformatics Institute (VBI) at Virginia Tech, in collaboration with the university's genetics, bioinformatics, and computational biology Ph.D. program, is providing substantial fellowships in support of graduate work in transdisciplinary team science. The Transdisciplinary Team Science Fellowship Program for the Life Sciences was developed for students interested in joining the Ph.D. program.
With the goal of connecting students with accomplished researchers working in a team-science environment, these fellowships cover the cost of the students' first two years in the program, which is $29,679 plus tuition and fees. After completion of their first two years of study, students will be supported by a research grant from their selected mentor professor.
The program is open to students with bachelor's degrees, and master's students, in particular, are strongly encouraged to apply. Recipients of the fellowship will be required to pursue projects at the interface of life and computational sciences as part of a transdisciplinary team.
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Chemist to donate potential pharmaceutical royalties to third-world nation
The National Institutes of Health has renewed a five-year research grant for a total of $2.5 million to an international biodiversity group led by University Distinguished Professor of Chemistry David G.I. Kingston, who is known internationally for his work in biodiversity and development of naturally occurring cancer-fighting agents. Consistent with the Convention on Biological Diversity, Kingston will share a portion of any royalties generated by sales of pharmaceuticals developed from this work with Madagascar, the country in which the research is taking place.
The award is the third competitive renewal of a research program that Kingston began in 1993. The grant was accompanied by a companion award from the U.S. Department of Agriculture of $1.25 million over the next five years. The overall goals of the International Cooperative Biodiversity Group are to foster biodiversity conservation, economic development, and drug discovery in Madagascar. The proposed research integrates the work of eight different research groups located in the United States and around the world.
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"TRUE LIFE: I'M A HOKIE"
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video contest winners announced
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The top three videos in the university's student YouTube video contest, "True Life: I'm a Hokie," were announced during the Virginia Tech versus University of Virginia football game on Nov. 29.
Capturing the spirit of the university with a distinctive take on Virginia Tech were first-place winner Tom Copenhaver, sophomore geography major in the College of Natural Resources; second-place winner Liz McClendon, a graduate student in the School of Education in the College of Liberal Arts and Human Sciences; and third-place winner Ian Heflin, a sophomore geosciences major in the College of Science. Copenhaver says that his music video highlighting many aspects of student life was definitely a team effort, with Spencer Ferguson, a sophomore chemistry major in the College of Science, composing the music, and Kevin Do, a sophomore in hospitality and tourism management in the Pamplin College of Business, writing the lyrics.
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The contest, which was designed with the help of university relations interns, junior Christie Lemley and senior Sarah Rothe, both communication majors in the College of Liberal Arts and Human Sciences, was launched to create excitement among students by giving them the ability to summarize, in video format, their personal perspective on what it is to be a Hokie and to build awareness of the university's YouTube site. The winners and all the submitted videos can be viewed at www.youtube.com/virginiatech. The site also includes historical videos that might be of interest to alumni. |
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Tiny bacteria weave big solutions
It sounds like a sci-fi version of the tale of the miller's daughter, but instead of turning straw into gold, bacteria are being used by Tech researchers to weave biomaterials and medical implants.
Acetobacter xylinum is a bacteria that produces cellulose nanofibers. About five years ago, Paul Gatenholm--then at Chalmers University of Technology in Sweden--discovered that the bacteria could weave those fibers to fit a template and that the resulting biomaterials were compatible with living tissue. To address the medical community's need for small blood vessels, Gatenholm's team at Chalmers had the bacteria produce tubes. By 2006, the scientists had developed a process for creating tubes of any size or shape.
Last year, Gatenholm--who has started three companies based on his findings at Chalmers--joined the Virginia Tech faculty as a professor of materials science and engineering, an affiliate of the Virginia Tech Center for Healing Biomaterials, and an adjunct faculty member with the Wake Forest University Institute for Regenerative Medicine. Here, Gatenholm met Rafael Davalos, an assistant professor of engineering science and mechanics, who had found that he could control bacteria motion using electrical fields. Supported by the Virginia Tech Institute for Critical Technology and Applied Science, Gatenholm and Davalos applied this technology to the cellulose-producing bacteria and soon had them shuttling back and forth like a nanoscale loom, assembling cellulose layers into custom 3-D architectures. As a result, the researchers can guide the bacteria toward templates that can support cartilage and bone tissue growth, among other complex biomaterials. The bacteria weave nanofibers around the structures, which are then placed within a living being.
One of Gatenholm's goals is the creation of cartilage--or, specifically, the creation of scaffolds that would be occupied by chondrocytes, the cells that produce cartilage. "We would build a porous scaffold in the shape of a nose or an ear as a structure for the chondrocytes to move into--in the body, not in a bioreactor," he explains. "The [bacterial cellulose] scaffold would be part of the healing process." Another unmet medical need is a way to replace large bone deficits, such as a piece of skull, without using metal implants. Gatenholm proposes constructing a bacterial cellulose scaffold to "create a material that allows the bone healing process to take place--or even stimulates it."
And patients could soon reap the benefits of the tiny weavers’ efforts for themselves. Virginia Tech Intellectual Properties Inc. has applied for a patent for Gatenholm and Davalos' "dielectrophorectic microweaving" technology, and a new company, BCGenesis, has been established in Blacksburg to provide biocompatible material for healing soft or hard connective tissue, such as bone grafts and cartilage replacement, and other orthopedic applications.
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Biomedical team obtains $4.9 million for trauma research
The Global Human Body Models Consortium, a group of nine international car manufacturers and suppliers, has awarded $4.9 million to the Center for Injury Biomechanics in the Virginia Tech-Wake Forest University School of Biomedical Engineering and Science, known internationally for its research on the effects of trauma on the human body.
The group is funding the Center for Injury Biomechanics to conduct a study that aims to produce a better understanding of what happens to individuals subjected to body trauma. "Initially, four sizes of individuals will be modeled to cover the maximum range of normal sizes in the world," says Joel Stitzel, associate professor of biomedical engineering at Wake Forest. The study will then branch out to include other body shapes and sizes, as well as differences for children and the elderly.
Better crash-safety technology is the ultimate goal of the consortium and participants. The computer models could help investigators determine and better understand injuries that are likely to result from a vehicle crash.
University partners with Apple, Mellanox to build green supercomputer
Five years ago, Virginia Tech burst onto the high-performance computing scene using Apple Power Mac G5 computers to build System X, one of the fastest supercomputers of its time. Today, Srinidhi Varadarajan and Kirk W. Cameron of the Center for High-End Computing Systems (CHECS) and professors of computer science in the College of Engineering have built a new supercomputer, System G. While the new supercomputer is twice as fast as its predecessor, the researchers' primary goal was to demonstrate that supercomputers can be both fast and have a more environmentally green technology. System G clocks in at 22.8 TFlops (or trillion operations per second) and consists of 325 Mac Pro computers, each with two 4-core 2.8 gigahertz (GHz) Intel Xeon processors and eight gigabytes (GB) random access memory (RAM). According to Cameron, System G has thousands of power and thermal sensors. As the world's largest power-aware cluster, System G will allow CHECS researchers to design and develop algorithms and systems software that achieve high-performance with modest power requirements and to test such systems at unprecedented scale.
Frank Lloyd Wright's work inspires design student's winning entry
Michelle Pyne, a fourth-year interior-design student in the School of Architecture + Design, has won a grand prize in the national JELD-WEN Student Door Design Contest.
JELD-WEN, a leading window and door manufacturer, selected Pyne's design from 349 entries from 89 colleges. Pyne received a $3,000 scholarship for her winning entry. Winners were selected based on suitability of the design for today's architecture, creativity, uniqueness, and attention to detail. Pyne's modern door was inspired by the work of Frank Lloyd Wright and his residential design for Ward M. Willitts in Chicago, featuring a symmetrical façade of stucco accented by thick wood strips.
Pyne says she plans to take the Leadership in Energy and Environmental Design examination soon after graduation and hopes to work in an architecture firm committed to sustainable design.
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For 14 years, Virginia Tech Alumni Distinguished Professor of History James I. Robertson Jr. delivered weekly commentaries on the Civil War on public radio stations in and around the Commonwealth of Virginia. This CD features 36 of Robertson's commentaries exploring the social history of the conflict.
"The Many Faces of the Civil War" is available at Virginia Tech's University Bookstore and Volume II Bookstore. Proceeds from the sale of the CD will support Virginia Center for Civil War Studies programs.
LISTEN to an excerpt from "Hardtack."
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